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The scope and purpose of this chapter is to examine system design considerations, and as a result, the individual unit operations and their potential impact on product quality will not be covered. The authors assume that each unit operation has been thoroughly investigated and is under sufficient control to do what it is purported to do. Specific effects of processing variables on product quality are dealt with the pertinent chapters in this book series.

A relatively few pharmaceutical products are prepared by true continuous-processing procedures whereby raw materials are continuously fed into and through the production sequence, and the finished product is continuously discharged from the final processing step. In continuous processing, one day’s production, the production from one work shift, the quantity of critical raw material from a given lot, or a combination thereof may define a single lot of manufactured products. Development of continuous-processing procedures requires specially designed and interfaced equipment,

Indian Pharmaceutical Manufacturer in Gujarat

OM Exim have the quality of the Indian Pharmaceutical Machinary Manufacturer in Ahmedabad Gujarat India. special plant layouts, and dedicated plant space, which reduces plant flexibility Indian Pharmaceutical Machinary in Ahmedabad. Indian Pharmaceutical Machinary Manufacturer, special plant design requirements, and dedicated space are all factors leading to the high costs of setting up and maintaining a continuous-manufacturing
operation for a product Indian Pharmaceutical Machinary in Ahmedabad.

Unless the volume of product being produced is very high, the cost of setting up a product-dedicated, continuous-production operation will not usually be justified. Since pharmaceutical products, even within a dosage-form class such as compressed Indian Pharmaceutical Machinary in Ahmedabad, differ materially in many important aspects, such as drug dosage, excipients used, critical factors, affecting product quality.

manufacturing problems, and the like, it is usually not feasible or possible to set up a continuous-processing operation for one product and then apply it to Indian Pharmaceutical Manufacturer in Gujarat. Thus true continuous-processing operations are largely limited in the drug industry to volume products, which often also have large doses (or high weights per tablet), such as Tums, Gelusil, Aldomet, or Alka Seltzer, Indian Pharmaceutical Manufacturer in Gujarat.

In either the batch or the continuous mode of operation, so the objective of production function is to produce pharmaceutical tablets for sale. Consequently, a production process should always be viewed as a candidate for progressive change in an effort to maintain the company’s products in the marketplace.

When looking at a process for possible changes, one must be aware of the potential benefits for the company Indian Pharmaceutical Manufacturer in Gujarat. The major benefits that can be obtained, and which constitute the major valid reasons for changing or redesigning a pharmaceutical tablet manufacturing process, are the following.

This can only be accomplished by a conscious effort on the part of those in process development. The development pharmacist should, therefore, be familiar with ways in which the manufacture of pharmaceutical products can be increased and labor reduced. Even though the development pharmacist will not be thoroughly knowledgeable in all areas of process design considerations Indian Pharmaceutical Manufacturer in Gujarat, he or she should at least be aware that those considerations exist and be able to interact with experts in those fields to Indian Pharmaceutical Machinary Manufacturer.

production unit impact on many other units also that come in contact with the production unit. However, with the rising costs of materials, labor, inflation, and regulations being constantly added to the manufacture of pharmaceuticals, the pharmaceutical industry cannot afford to neglect change or the modification of existing processes simply because there are established standards that may be difficult to change. Increased productivity matched with a reduction in direct labor cost will probably be the way of the Indian Pharmaceutical Manufacturer in Gujarat.

This can only be accomplished by a conscious effort on the part of those in process development. The development pharmacist should, therefore, be familiar with ways in which the manufacture of pharmaceutical products can be increased and labor reduced Indian Machinary Manufacturer in India. Even though
the development pharmacist will not be thoroughly knowledgeable in all areas of process design considerations, he or she should at least be aware that those considerations exist and be able to Pharmaceutical Machinary Manufacturers.

Possibly the single largest contribution to the effectiveness of a manufacturing facility is made by the facility’s materials-handling capabilities. In addition to a lack of Indian Pharmaceutical Machinary Manufacturer,

There are certain risks involved with improper or inefficient materials Indian Machinary Manufacturer in India. These risks include increased product costs, Pharmaceutical Machinary Manufacturers so Indian Pharmaceutical Machinary Manufacturer, and employee safety liabilities. Materials that are not handled efficiently can increase the cost of raw materials.

Indian Pharmaceutical Machinary Manufacturer well-designed and efficiently operated materials-handling system should impart to the manufacturing facility reduced handling costs, increased manufacturing capacity. improved working conditions Indian Pharmaceutical Machinary Manufacturer. and improved raw material distribution to the appropriate manufacturing areas Indian Machinary Manufacturer in India. To achieve an efficient materials-handling system. as many of the basic general principles of efficient materials handling need to be Pharmaceutical Machinary Manufacturers.

The transportation mechanism for raw materials should never be an Indian Machinary Manufacturer in India. For example. if tablet-packaging materials are being transported from a warehouse to a packaging line by means of a fork-lift truck. the return trip could Indian Pharmaceutical Machinary Manufacturer, for example, for the removal of accumulated scrap material or a finished product from the production line Indian Machinary Manufacturer in India.

How a company designs its materials-handling facility and its production process is based on several different considerations. The type of process that is being designed, batch, or continuous Pharmaceutical Machinary Manufacturers; will have a great influence on the type of materials handling system used. The materials-handling system in a batch-oriented, multiproduct facility is significantly different from a single-product, continuous-process. materials-handling system.

The type and quantity of products as well as the physical characteristics of the raw materials involved will also affect the materials-handling system. For example, fluids for granulating will have to be pumped, whereas solids will have to be handled in another manner,

such as with vacuum devices Pharmaceutical Machinary Manufacturers. The type of building that is available for the manufacturing process may exert the single greatest influence on the materials-handling Indian Pharmaceutical Machinary Manufacturer. The lack of a multistoried building will preclude the use gravity for material flow. Like all company decisions. the costs of purchase.

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60, Gokul Duplex Near Haridarshan Cross, Kathwada Road,Nava Naroda, Ahmedabad-382330,Gujarat,India.

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